POLYCLONAL SYNAPTOPHYSIN

Code: 336A-74 D2-231

General description

Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal...


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General description

Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, Paneth cells in the gastrointestinal tract, and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Anti-synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Linkage

Synaptophysin Positive Control Slides , Product No. 336S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Other Notes

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Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide

Preparation Note

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antibody formIg fraction of antiserum
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
conjugateunconjugated
controlpancreas
descriptionFor In Vitro Diagnostic Use in Select Regions (See Chart)
formbuffered aqueous solution
Gene Informationhuman ... SYP(6855)
manufacturer/tradenameCell Marque
packagingvial of 0.5 mL concentrate (336A-75), vial of 1.0 mL concentrate (336A-76), vial of 0.1 mL concentrate (336A-74), bottle of 1.0 mL predilute (336A-77), bottle of 7.0 mL predilute (336A-78)
Quality Level100, 500
shipped inwet ice
species reactivityhuman
storage temp.2-8°C
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
visualizationcytoplasmic
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